In vitro and in vivo evaluation of a bioactive polysaccharide based self-healing hydrogel film for enhanced wound healing

Ayan Ranjan Hati, Chalamala Balagangadhar Reddy, Purnendu Ghosh, Kaushik Mukherjee, Amalesh Samanta, Samit Kumar Nandi, Tapan Kumar Giri, Department of Pharmaceutical Technology, Jadavpur University, Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences

Journal of Biomaterials Applications

Published online on July 30, 2026

Abstract

Journal of Biomaterials Applications, Ahead of Print.
The objective of this research was to develop a carboxymethyl chitosan (CMCS) loaded borax cross-linked guar gum (GG) self-healing hydrogel film dressing for enhanced wound healing. Cross-links between borax and GG were confirmed through FTIR, SEM, and ...