["Business Strategy and the Environment, EarlyView. ", "\nABSTRACT\nThis research develops an integrated mixed‐integer linear programming (MILP) model for closed‐loop supply chain network design that optimises competing economic and environmental objectives including profit maximisation, supplier quality improvement and CO2 emission reduction. The primary aim of this study is to identify which solution techniques perform best when dealing with different sizes of problems. The multi‐objective particle swarm optimisation (MOPSO) method demonstrated superior performance over NSGA‐II by achieving 35%–45% faster convergence rates and delivering 20%–30% better solution quality. The epsilon‐constraint approach with CPLEX showed better performance for solving smaller problems. The analysis revealed that return rates, together with material recovery expenses, function as essential elements which determine the profitability of the disassembly process. The research proves that multi‐objective optimisation methods work efficiently with real supply chain sizes. These findings support the development of decision support systems for sustainable operations management.\n"]