Preparation and performance study of strontium-carboxymethyl chitosan/silk fibroin/gelatin composite cartilage scaffolds

Changcheng Wang, Mingxi Gu, Tianyi Song, Xiaochen Wang, Lin Guo, Fengde Tian, Bo Liu, Dewei Zhao, Faculty of Medicine, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Department of Orthopedics, Affiliated Zhongshan Hospital of Dalian University, Department of Internal Medicine, Peking University Shenzhen Hospital, Department of Reparative and Reconstructive Surgery, Peking University Shougang Hospital

Journal of Biomaterials Applications

Published online on March 30, 2026

Abstract

Journal of Biomaterials Applications, Ahead of Print.
Objective: Articular cartilage exhibits extremely poor self-repair capacity, often leading to osteoarthritis. This study aims to develop a strontium-containing porous composite cartilage scaffold (CMCS-Sr-Gel-SF) that combines bioactivity with mechanical ...