This study confirmed the reliability and validity of the Quality Indicators of Exemplary Transition Programs Needs Assessment–2 (QI-2). Quality transition program indicators were identified through a systematic synthesis of transition research, policies, and program evaluation measures. To verify reliability and validity of the QI-2, we administered rigorous methods including a content analysis, an expert review, and instrument field test. Forty-seven indicators were categorized into seven domains: (a) transition planning, (b) transition assessment, (c) family involvement, (d) student involvement, (e) transition-focused curriculum and instruction, (f) interagency collaboration, and (g) systems-level infrastructure. The QI-2 was found to be reliable and valid for use by transition stakeholders, districts, and states for evaluating quality of transition programs and identifying areas for program improvement.