The purpose of this longitudinal study of 255 members of the low-skilled workforce was to enhance insight into the nature of the relations between specific supervisor behavior (social support, positive feedback, task-related communication) and employee well-being. Data were analyzed using latent change models focusing on interindividual change and change–change associations over time. Our results indicated that interindividual differences in the intraindividual change in perceived supervisor behavior were related to changes in indicators of well-being across a 6-month period. These results provide further evidence for longitudinal associations between leader behavior and employee outcomes as well as the necessity of designing specific interventions for low-level managers.