Del Nido cardioplegia is a cost-effective alternative to custodiol for myocardial protection in aortic valve surgery: A real-world study

Kevin Maldonado-Cañón, Silvia Alejandra Prada Liévano, Héctor Olaya, Valentina Pérez-Ariza, Andrés Felipe Barrera Vargas, Juan Andrés Sarmiento, Andrés Motta, Carlos Pérez Rivera, Nicolás Forero, Santiago Niño, Javier Maldonado-Escalante, Grupo de Investigación en Cirugía Cardiovascular, Clínica Universitaria Colombia, Department of Clinical Epidemiology and Biostatistics, PhD Program in Clinical Epidemiology, Pontificia Universidad Javeriana, Cardiovascular Surgery Section, Department of Surgery, Clínica Universitaria Colombia, School of Medicine, Universidad de los Andes, Department of Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, Department of Surgery, Fundación Santa Fe de Bogotá

Perfusion

Published online on August 12, 2026

Abstract

Perfusion, Ahead of Print.
IntroductionMyocardial protection is crucial in heart surgery to minimize ischemia-reperfusion injury. Del Nido cardioplegia has demonstrated clinical advantages; however, cost-effectiveness data over Custodiol remain scarce. We aimed to assess whether ...