Efficacy and Safety of Tesamorelin in People Living With HIV (PLWH) With Lipodystrophy: A Systematic Review and Meta-Analysis

Aqsa Mohammed Ditta, Ruqaiya Muhammad Naeem, Muhammad Mohsin Sami, Muhammad Abdul Rafey, Hunain Ali, Muhammad Waqar Amjad, Fahad Jahangir, Kehan Ali Rizvi, Fatima Mohammad, Husam Abu Dawood, Muhammad Suleman, Muhammad Nabeel Saddique, Faculty of Medicine, Rawalpindi Medical University, Faculty of Medicine, Sargodha Medical College, Faculty of Medicine, University of South China, Faculty of Medicine, Shaheed Zulfiqar Ali Bhutto Medical University, Faculty of Medicine, Karachi Medical and Dental College, Faculty of Medicine, Sahiwal Medical College, Faculty of Medicine, Palestine Polytechnic University, Palestinian Territory, Faculty of Medicine, King Edward Medical University

Journal of the International Association of Providers of AIDS Care (JIAPAC)

Published online on August 01, 2026

Abstract

Journal of the International Association of Providers of AIDS Care (JIAPAC), Volume 25, January-December 2026.
BackgroundHIV-associated lipodystrophy, a complication of combined antiretroviral therapy (CART), causes significant physical and psychological distress in people living with HIV (PLWH), compromising treatment adherence. Tesamorelin, a growth hormone-...