Clinical Efficacy and Brain Volumetric Changes in Pediatric-Onset Multiple Sclerosis Under Teriflunomide Treatment

Zeynep Öztürk, Merve Yazol, Huriye Çetin, Esra Serdaroğlu, Ebru Arhan, Tuğba Hirfanoğlu, Kıvılcım Gücüyener, Öznur Leman Boyunağa, Ercan Demir

Journal of Child Neurology

Published online on July 28, 2026

Abstract

Journal of Child Neurology, Ahead of Print.
BackgroundBrain volumetric imaging provides important insights into neuroaxonal injury in pediatric-onset multiple sclerosis (POMS), beyond conventional clinical measures of disease activity.ObjectiveTo evaluate the longitudinal brain volume changes in ...