Transcriptome-wide m6A Methylation Profiling Reveals Regulatory Networks During Endothelial Differentiation of Bone Marrow Mesenchymal Stem Cells

Ziping Yao, Bihui Zhang, Yinghua Zou, Xiaoqiang Tong, Ziguang Yan, Guochen Niu, Yuan Li, Min Yang, Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Department of Hematology, Peking University First Hospital

Clinical and Applied Thrombosis/Hemostasis

Published online on July 25, 2026

Abstract

Clinical and Applied Thrombosis/Hemostasis, Volume 32, January-December 2026.
BackgroundMesenchymal stem cell (MSC)-derived endothelial-like cells exhibit enhanced angiogenic potential compared with undifferentiated MSCs. However, the role of N6-methyladenosine (m6A) RNA modification in MSC endothelial differentiation remains ...