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Development of a tissue-based risk prediction model combining histology and barrier biomarkers for clinical relapse in ulcerative colitis with endoscopic healing

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Therapeutic Advances in Gastroenterology

Published online on

Abstract

Therapeutic Advances in Gastroenterology, Volume 19, January-December 2026.
Background:Although endoscopic remission is a primary therapeutic target in ulcerative colitis (UC), a meaningful proportion of patients with endoscopic healing still experience clinical relapse (CR). Histologic activity and epithelial barrier dysfunction ...