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T-bet expression in B cell subsets: Association with T peripheral helper cells and clinical activity in systemic lupus erythematosus

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Lupus: An International Journal

Published online on

Abstract

Lupus, Ahead of Print.
BackgroundSystemic lupus erythematosus (SLE) features aberrant T-B cooperation and expansion of atypical memory B cells (aMBCs) characterized by the expression of CD11c and T-bet. We investigated the relationship between IL-21/IL-21R and the activation ...