Smoking Cessation in Primary Care: A Narrative Review of Evidence-Based Treatment, Emerging Technology, and Harm Reduction Approaches

Ivana T. Croghan, Ryan T. Hurt, Muhamad Y. Elrashidi, Timothy J. Milbrandt, Aditya K. Ghosh, Shawn C. Fokken, Jon O. Ebbert, Department of Medicine, Division of General Internal Medicine, Mayo Clinic, Department of Medicine, Division of Community Internal Medicine, Geriatrics and Palliative Care, Mayo Clinic, Department of Medicine, Nicotine Dependence Center, Mayo Clinic, Department of Quantitative Health Science, Division of Clinical Trials and Biostatistics, Mayo Clinic

Journal of Primary Care & Community Health

Published online on July 13, 2026

Abstract

Journal of Primary Care & Community Health, Volume 17, January-December 2026.
Conventional cigarette smoking remains a leading preventable cause of morbidity and mortality despite declining prevalence, yet evidence-based treatments remain underused. This narrative review examines guideline-supported therapies and emerging ...