Acute and Chronic Toxicity Assessment of Diosgenin Polyethylene Glycol Succinate in Wistar Rats: Safety Evaluation of a Novel Universal Solubilizer

Varsha Velmurugan, Velmurugan Shanmugham, Thangamani Arumugam, Department of Research and Development, Phytosol India Private Limited, Department of Chemistry, Karpagam Academy of Higher Education

International Journal of Toxicology

Published online on July 21, 2026

Abstract

International Journal of Toxicology, Ahead of Print.
Diosgenin, derived fromDioscorea alata, is a well-known traditional medicinal compound with therapeutic potential against various conditions, including cancer and cardiovascular diseases. This study aimed to synthesize diosgenin polyethylene glycol ...