The End of “Benign”: Drivers of the ICD-O Code Upgrade for Pituitary Neuroendocrine Tumors and the Molecular Revolution
International Journal of Surgical Pathology
Published online on July 14, 2026
Abstract
International Journal of Surgical Pathology, Ahead of Print.
The International Classification of Diseases for Oncology (ICD-O) behavior code for pituitary neuroendocrine tumors (PitNETs) underwent a historic shift from “/0” (benign) to “/3” (primary malignant) in the 2022 fifth edition of the WHO classification. ...
The International Classification of Diseases for Oncology (ICD-O) behavior code for pituitary neuroendocrine tumors (PitNETs) underwent a historic shift from “/0” (benign) to “/3” (primary malignant) in the 2022 fifth edition of the WHO classification. ...