A nonhydrolyzable candesartan cilexetil analog reveals synergistic activation as a tractable mechanism for TMEM175 modulation

Kangjun Li, Samantha D. Le, Vaishali Satpute Janve, Roman M. Lazarenko, Ian M. Romaine, Kwangho Kim, Gary A. Sulikowski, Alex G. Waterson, Jerod S. Denton

AJP Cell Physiology

Published online on July 21, 2026

Abstract

American Journal of Physiology-Cell Physiology, Volume 331, Issue 2, Page C415-C424, August 2026.