Novel FLCN mutations in Birt-Hogg-Dubé patients and potential intervention of FLCN mRNA
Therapeutic Advances in Respiratory Disease
Published online on May 28, 2026
Abstract
Therapeutic Advances in Respiratory Disease, Volume 20, January-December 2026.
Background:Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant disorder caused by folliculin (FLCN) gene mutations, with ethnically heterogeneous mutational spectra. Current management is primarily supportive and lacks curative therapies.Objectives:...
Background:Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant disorder caused by folliculin (FLCN) gene mutations, with ethnically heterogeneous mutational spectra. Current management is primarily supportive and lacks curative therapies.Objectives:...