An inverse probability of treatment weighted comparison between vedolizumab, ustekinumab, and tofacitinib in anti-TNF-experienced ulcerative colitis patients

Antonio Tursi, Andrea Pasta, Walter Elisei, Brigida Barberio, Luisa Bertin, Giammarco Mocci, Giovanni Maconi, Antonietta Gerarda Gravina, Raffaele Pellegrino, Giorgia Bodini, Alfredo Papa, Edoardo Vincenzo Savarino

Therapeutic Advances in Gastroenterology

Published online on June 15, 2026

Abstract

Therapeutic Advances in Gastroenterology, Volume 19, January-December 2026.
Background:Biologics and small-molecule therapies are widely used for ulcerative colitis (UC), but their comparative effectiveness in anti-tumor necrosis factor (TNF)-exposed patients is unclear.Objectives:To compare the effectiveness and safety of ...