Genome-Wide Association Study of African and European Populations with Anterior Cruciate Ligament Injury

Casey Kuka, Matt Titus, Monika Thothadri, Divya Talwar, Kevin Landrum, Hui-Qi Qu, Margaret Harr, Brendon Mitchell, Joseph Yellin, Syreeta Morgan, Hakon Hakonarson, Theodore Ganley

Orthopaedic Journal of Sports Medicine

Published online on June 17, 2026

Abstract

Orthopaedic Journal of Sports Medicine, Volume 14, Issue 6_suppl5, June 2026.
Background:Anterior cruciate ligament (ACL) injuries are one of the most common pediatric knee injuries requiring surgery. Evolutionary genetic signatures in human populations enable the genome-wide association study (GWAS) approach to identify ...