Functional Motor Change Across Time and Phenotypes in Patients With Amyotrophic Lateral Sclerosis: A Descriptive Study

Elissa C. Held-Bradford, Elisabeth DeMarco, Samantha Zocher, Kate Weaver, Kathryn Forsman, Ghazala Hayat, Divya S. Subramaniam, Meghan Doherty

Neurorehabilitation and Neural Repair: An International Journal of Translational Science for Researchers and Clinicians

Published online on June 10, 2026

Abstract

Neurorehabilitation and Neural Repair, Ahead of Print.
Purpose:Progressive disability occurs in persons with amyotrophic lateral sclerosis (pALS), but change over time across phenotypes remains understudied, limiting clinical decision-making. This descriptive study describes functional motor change with ...