Single-cell sequencing in systemic lupus erythematosus

Anrui Yu, Jingyi Wu, Dehao Zhu, Xia Lin, Yuyang Ren, Chengde Yang, Zhuochao Zhou, Junna Ye, Department of Rheumatology and Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Pediatrics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Lupus: An International Journal

Published online on June 03, 2026

Abstract

Lupus, Ahead of Print.
BackgroundSystemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by heterogeneous clinical manifestations and multi-organ involvement. Current understanding of SLE pathogenesis remains limited, particularly due to the cellular ...