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Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice

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Integrative Cancer Therapies

Published online on

Abstract

Integrative Cancer Therapies, Volume 25, January-December 2026.
Irinotecan (IRI), a clinically used anticancer drug, is effective against various solid tumors, including colorectal cancer, but its use is limited by side effects. Triptolide (TP), an alkaloid fromTripterygium wilfordii, has been used to treat ...