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Neoadjuvant therapy versus upfront surgery followed by adjuvant chemotherapy in resectable or borderline resectable PDAC: a systematic review and meta-analysis of RCTs

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Therapeutic Advances in Medical Oncology

Published online on

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Background:Adjuvant chemotherapy remains the standard of care following resection of pancreatic ductal adenocarcinoma (PDAC). However, despite advances with modern multi-agent regimens, most patients relapse, underscoring the need for alternative ...