The type 2 deiodinase Thr92Ala polymorphism and cognitive aging: current evidence and biological context
Therapeutic Advances in Endocrinology and Metabolism
Published online on May 11, 2026
Abstract
Therapeutic Advances in Endocrinology and Metabolism, Volume 17, January-December 2026.
Type 2 iodothyronine deiodinase (DIO2) plays a central role in regulating thyroid hormone (TH) metabolism in the brain by catalyzing the conversion of thyroxine (T4) to the active triiodothyronine (T3), thereby ensuring adequate local TH signaling in ...
Type 2 iodothyronine deiodinase (DIO2) plays a central role in regulating thyroid hormone (TH) metabolism in the brain by catalyzing the conversion of thyroxine (T4) to the active triiodothyronine (T3), thereby ensuring adequate local TH signaling in ...