Lower-dose glucocorticoid therapy achieves comparable outcomes in Japanese patients with lupus nephritis
Yoshiyuki Abe,
Ayako Makiyama,
Kentaro Minowa,
Saki Uchiyama,
Masahiro Kogami,
Motoki Takeuchi,
Yoshiya Tanaka,
Keiju Hiromura,
Hiroki Hayashi,
Kazuro Kamada,
Yutaka Kawahito,
Akiho Iwashita,
Shinya Kaname,
Hayato Shimizu,
Shinsuke Yasuda,
Kazuoto Hiramoto,
Shoichi Maruyama,
Nobuyuki Yajima,
Yasunori Iwata,
Isao Matsumoto,
Takahisa Gono,
Hiroko Sato,
Satoshi Kubo,
Hidekazu Ikeuchi,
Yukio Yuzawa,
Michihito Kono,
Takahiro Seno,
Akira Onishi,
Takahisa Kawakami,
Tadashi Hosoya,
Yuko Kaneko,
Sawako Kato,
Shiori Nakagawa,
Yuya Kondo,
Masataka Kuwana,
Tomonori Ishii,
Tatsuya Atsumi,
Koichiro Ohmura,
Naoto Tamura,
Department of Internal Medicine and Rheumatology,
Juntendo UniversitySchool of Medicine,
Clinical Research and Trial Center,
Juntendo UniversityHospital,
The First Department of Internal Medicine,
University of Occupational and Environmental Health,
Department of Nephrology and Rheumatology,
Gunma UniversityGraduate School of Medicine,
Department of Nephrology,
Fujita Health University School of Medicine,
Department of Rheumatology,
Endocrinology and Nephrology,
Faculty of Medicine and Graduate School of Medicine,
Hokkaido University,
Inflammation and Immunology,
Kyoto Prefectural University of Medicine,
Department of Rheumatology and Clinical Immunology,
Kyoto UniversityGraduate School of Medicine,
Department of Nephrology and Rheumatology,
Kyorin UniversitySchool of Medicine,
Department of Internal Medicine,
Kichijoji Asahi Hospital,
Department of Rheumatology,
Kobe City Medical Center General Hospital,
Department of General Internal Medicine,
Kobe City Medical Center General Hospital,
Department of Rheumatology,
Institute of Science Tokyo,
Division of Rheumatology,
Department of Internal Medicine,
Keio UniversitySchool of Medicine,
Department of Nephrology,
Nagoya UniversityGraduate School of Medicine,
Division of Rheumatology,
Department of Medicine,
Showa Medical University,
Department of Nephrology and Rheumatology,
Kanazawa University,
Department of Rheumatology,
Institute of Medicine,
University of Tsukuba,
Department of Allergy and Rheumatology,
Nippon Medical SchoolGraduate School of Medicine,
Myositis Center of Excellence,
Nippon Medical SchoolHospital,
Department of Rheumatology,
Tohoku UniversityHospital,
Department of Advanced Medicine for Rheumatic Diseases,
Kyoto UniversityGraduate School of Medicine,
Tohoku Medical and Pharmaceutical University Hospital
Lupus: An International Journal
Published online on May 06, 2026
Lupus, Volume 35, Issue 8, Page 831-841, July 2026.
ObjectiveTo evaluate the effectiveness of a lower initial glucocorticoid (GC) dose (0.4–0.6 mg/kg/day) compared to the conventional dose (0.8–1.2 mg/kg/day) in achieving complete renal response (CRR) at 12 months in Japanese patients with proliferative ...