Dapagliflozin ameliorates high-fat diet–induced, megalin-mediated autolysosomal dysfunction in proximal tubules via suppression of megalin-dependent endocytosis

Kazuya Takemoto, Michihiro Hosojima, Hideyuki Kabasawa, Koichi Komochi, Hiroyuki Aoki, Nanako Sugita, Sawako Goto, Ryohei Kaseda, Satoru Nagatoishi, Kouhei Tsumoto, Ichiei Narita, Suguru Yamamoto, Akihiko Saito

Renal Physiology

Published online on April 29, 2026