Improvement of glucose homeostasis during leptin treatment does not alter the intestinal microbiome in male diabetic UC Davis type-2 diabetes mellitus rats

Manuel Martínez-Ruiz, Leslie Tabor-Simecka, James L. Graham, Christopher Randolph, Renee Fox, Renny Lan, Lindsay Pack, Tanya LeRoith, Kimber L. Stanhope, Laxmi Yeruva, Peter J. Havel, Brian D. Piccolo

AJP Gastrointestinal and Liver Physiology

Published online on April 23, 2026

Abstract

American Journal of Physiology-Gastrointestinal and Liver Physiology, Volume 330, Issue 5, Page G549-G564, May 2026.