Pathology associated with human CAR T cell administration in NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG) mice: A retrospective analysis
Published online on January 28, 2026
Abstract
Veterinary Pathology, Volume 63, Issue 3, Page 462-477, May 2026.
Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for neoplasia and autoimmune diseases. Immunocompromised mice are a common model to test the efficacy and safety of CAR T cells of human origin. Preclinical toxicity associated with ...
Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for neoplasia and autoimmune diseases. Immunocompromised mice are a common model to test the efficacy and safety of CAR T cells of human origin. Preclinical toxicity associated with ...