Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs
Published online on March 05, 2026
Abstract
Veterinary Pathology, Volume 63, Issue 3, Page 445-461, May 2026.
Humanized mice engrafted with human CD34+ hematopoietic stem cells (HSCs) are invaluable models for the preclinical evaluation of cancer immunotherapy drugs, helping to bridge the gap betweenin vitrostudies and clinical trials. However, there are ...
Humanized mice engrafted with human CD34+ hematopoietic stem cells (HSCs) are invaluable models for the preclinical evaluation of cancer immunotherapy drugs, helping to bridge the gap betweenin vitrostudies and clinical trials. However, there are ...