Carcinogenicity Risk Assessment of Targeted Protein Degraders
Published online on April 29, 2026
Abstract
Toxicologic Pathology, Ahead of Print.
Targeted protein degraders (TPDs) have recently emerged as a novel drug class. Targeted protein degraders engage E3 ubiquitin ligase complexes to degrade therapeutic proteins of interest via cereblon and other adapter proteins, acting as either molecular ...
Targeted protein degraders (TPDs) have recently emerged as a novel drug class. Targeted protein degraders engage E3 ubiquitin ligase complexes to degrade therapeutic proteins of interest via cereblon and other adapter proteins, acting as either molecular ...