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Positioning siponimod and the post-treatment gap: the unmet needs of SPMS patients in Italian real-world practice

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Therapeutic Advances in Neurological Disorders

Published online on

Abstract

Therapeutic Advances in Neurological Disorders, Volume 19, January-December 2026.
Background:Siponimod, a selective sphingosine-1-phosphate receptor modulator was approved for patients with Secondary progressive Multiple Sclerosis (SPMS) with ongoing disease activity. However, its real-world positioning and management after ...