The clinical phenotype of anti-Th/To+ patients in systemic sclerosis: a case-control study within the European Scleroderma Trials and Research cohort

Liala Moschetti, Silvia Rovaris, Francesco Bonomi, Helena Codes-Mendez, María Martín-López, Fabio Cacciapaglia, Antonio Tonutti, Francesco Del Galdo, Corrado Campochiaro, Marie Elise Truchetet, Yannick Allanore, Masataka Kuwana, Cosimo Bruni, Cristiana Sieiro Santos, Gianluca Moroncini, Joana Caetano, Brigitte Granel, Laura Groseanu, Eleonora Pedretti, Enrico Colombo, Miriam Guerini, Mariana Pereira Silva, Pietro Bearzi, Laura Belloli, Juan Jose Alegre-Sancho, Cristina Maglio, Giovanna Cuomo, Magda Parvu, Hadi Poormoghim, Luca Idolazzi, Kristofer Andréasson, Maria De Santis, Florenzo Iannone, Patricia Esmeralda Carreira, Ivan Castellví, Serena Guiducci, Ilaria Cavazzana, Franco Franceschini, Paolo Airò, Maria Grazia Lazzaroni

Therapeutic Advances in Musculoskeletal Disease

Published online on March 02, 2026

Abstract

Therapeutic Advances in Musculoskeletal Disease, Volume 18, January-December 2026.
Background:Systemic sclerosis (SSc) is a heterogeneous autoimmune disease, where autoantibody profiling plays a central role in defining disease subsets and guiding personalized management.Objectives:To investigate the clinical phenotype and long-term ...