Serum interleukin-8 levels relate to disease activity in patients with rheumatoid arthritis

Diamela León-Cabrera, Juan C. Quevedo-Abeledo, Cristina Almeida-Santiago, Enrique García-Barrera, Luisa M. Villar, Patricia Quiroga-Colina, Javier Gonzalo Ocejo-Vinyals, Alberto Javier-Ormazábal, Miguel Á. González-Gay, Iván Ferraz-Amaro

Therapeutic Advances in Musculoskeletal Disease

Published online on April 20, 2026

Abstract

Therapeutic Advances in Musculoskeletal Disease, Volume 18, January-December 2026.
Background:Interleukin 8 (IL-8) is a chemokine involved in the pathogenesis of rheumatoid arthritis (RA). However, the clinical significance of its circulating levels remains poorly defined, partly due to technical challenges in measuring IL-8 in serum. ...