The role of thoracic radiotherapy in the setting of immunotherapy in polymetastatic esophageal squamous cell carcinoma: a multi-center cohort study

Qi Liu, Junqiang Chen, Wenbin Shen, Jinjun Ye, Honglei Luo, Xizhi Zhang, Wenyang Liu, Yujin Xu, Yingying Zhang, Anwen Liu, Xiaopeng Li, Hong Ge, Qifeng Wang, Hui Luo, Lina Zhao, Conghua Xie, Qin Lin, Congying Xie, Luhua Wang, Kuaile Zhao

Therapeutic Advances in Medical Oncology

Published online on February 12, 2026

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Background:The efficacy of immunochemotherapy (ICT) remains poor in patients with polymetastases from esophageal squamous cell carcinoma (ESCC). While radiation therapy (RT) has shown promise in oligometastatic settings, its role when combined with ICT ...