Clinical subtypes in breast cancer patients with brain metastases from an ambispective registry of advanced breast cancer, GEICAM/2014-03 (RegistEM)

Sara López-Tarruella, Ángel Guerrero-Zotano, Silvia Antolín, Josefina Cruz, Purificación Martínez, César A. Rodríguez, Catalina Falo, Álvaro Rodríguez-Lescure, Encarna Adrover, María Hernández, Raquel Andrés, José Ignacio Chacón, José Luis Alonso Romero, Ana Miguel, César Gómez-Raposo, Mireia Margelí, Iria González, Juan Antonio Guerra, Antonio Antón, Ariadna Tibau, Juan José Miralles, María José Escudero, Susana Bezares, Federico Rojo, Isabel Álvarez

Therapeutic Advances in Medical Oncology

Published online on February 20, 2026

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Background:Breast cancer frequently results in brain metastases (BCBM), leading to poor outcomes. Central nervous system (CNS) involvement entails significant challenges in advanced breast cancer (ABC) patients.Objectives:To characterize BCBM patients ...