Impact of relative dose intensity of first-line platinum-based chemotherapy in patients with thymic epithelial tumors: a retrospective study

Erica Pietroluongo, Pietro De Placido, Roberto Buonaiuto, Aldo Caltavituro, Giuseppe Neola, Margaret Ottaviano, Marianna Tortora, Grazia Arpino, Giovannella Palmieri, Carmine De Angelis, Marina Chiara Garassino, Roberto Bianco, Alberto Servetto, Mario Giuliano

Therapeutic Advances in Medical Oncology

Published online on February 13, 2026

Abstract

Therapeutic Advances in Medical Oncology, Volume 18, January-December 2026.
Background:Platinum-based chemotherapy is the first-line treatment choice for advanced thymic epithelial tumors (TETs), with the expected objective response rate (ORR) ≈of 50% in thymoma and ≈20% in thymic carcinoma.Objective:To evaluate the impact of ...