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Neutrophil-to-lymphocyte ratio half reduction as a surrogate of molecular response in polycythemia vera treated with ropeginterferon alfa-2b

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Therapeutic Advances in Hematology

Published online on

Abstract

Therapeutic Advances in Hematology, Volume 17, January-December 2026.
Background:Polycythemia vera (PV) is a myeloproliferative neoplasm driven byJAK2V617F mutations. Ropeginterferon alfa-2b effectively reduces both hematologic parameters andJAK2allele burden, but molecular monitoring is not always readily available....