A Novel Plasma Microscalpel Based on Airplasma® Technology. A Histological Analysis of Brain Tissue Damage

Francesco Guerrini, Alessandra Viglio, Cesare Zoia, Valeria Musella, Pietro Serinelli, Catherine Klersy, Pietro Zangrossi, Viola Marta Custodi, Erika Ferrari, Giuseppe Bellantoni, Francesco Salomi, Giannantonio Spena, Unit of Neurosurgery, Department of Head , Neck Surgery, Fondazione IRCCS Policlinico San Matteo, Department of Internal Medicine, University of Pavia, Unit of Pathology, Department of Diagnostic and Laboratory Medicine, Fondazione IRCCS Policlinico San Matteo, Unit of Neurosurgery, Moriggia-Pelascini Hospital, Unit of Biostatistics and Clinical Trial Center, Fondazione Policlinico IRCCS San Matteo, Department of Neurosurgery, Anna University Hospital and Department of Translational Medicine, University of Ferrara

Surgical Innovation

Published online on April 20, 2026

Abstract

Surgical Innovation, Ahead of Print.
BackgroundMicroscalpel based upon Airplasma® technology showed promising results in dermatology, plastic surgery and veterinary in terms of tissue lateral thermal damage (LTI). In this preclinical work, we aimed to explore its effect on central nervous ...