Implementing response-adaptive designs when responses are missing: Impute or ignore?
Statistical Methods in Medical Research: An International Review Journal
Published online on August 29, 2025
Abstract
Statistical Methods in Medical Research, Ahead of Print.
Missing data is a widespread issue in clinical trials, but is particularly problematic for digital health interventions where disengagement is common and outcomes are likely to be missing not at random (MNAR). Trials that use response-adaptive designs ...
Missing data is a widespread issue in clinical trials, but is particularly problematic for digital health interventions where disengagement is common and outcomes are likely to be missing not at random (MNAR). Trials that use response-adaptive designs ...