Compression versus bridge negative pressure wound therapy combined with compression in non-healing venous ulcers: A randomized controlled trial with quality-of-life assessment and cost effectiveness

Wael Tawfick, Yogesh Acharya, Kalliopi-Maria Tasopoulou, Marion Cahill-Collins, William Wijns, Nicole Gallagher, Osama Soliman, Sherif Sultan, Department of Vascular and Endovascular Surgery, University Hospital Galway, University of Galway, School of Medicine, University of Galway, Department of Vascular Surgery and Endovascular Surgery, Galway Clinic, Western Vascular Institute, Royal College of Surgeons in Ireland and University of Galway, Galway Affiliated Hospital, The Lambe Institute for Translational Medicine and Curam, University of Galway, Precision Cardiovascular Medicine , Innovation Institute , Cardiovascular Research Institute Dublin , CVRI Dublin, Mater Private Network , RCSI University of Medicine and Health Sciences

Phlebology: The Journal of Venous Disease

Published online on November 28, 2025

Abstract

Phlebology, Ahead of Print.
ObjectivesNegative pressure wound therapy (NPWT) is a useful adjunct to optimization of wound healing. We aimed to evaluate the benefits of NPWT in the management of refractory non-healing venous leg ulcers (VLU), in conjunction with compression therapy (...