Non thermal HIFU treatment for vein occlusion: Histological evidence from a pre-clinical animal study

Olivier Pichot, Alice Ganeau, Pierre Combes, Charlotte Millet, Valentin Derangère, Cyril Lafon, Department of Vascular Medicine, Groupement Hospitalier Mutualiste, D Department, Clinique Aguiléra, Centre de Recherche Inserm, Ctm U, UFR Sciences de Santé, Université de Bourgogne, Centre Léon Bérard, Université Claude Bernard Lyon

Phlebology: The Journal of Venous Disease

Published online on November 29, 2025

Abstract

Phlebology, Ahead of Print.
ObjectiveThe aim of this preclinical study is to investigate in-vivo veins effects including histological analysis following endovenous cavitation by Non-Thermal High-Intensity Focused Ultrasound (NT-HIFU).MethodsFour lateral saphenous veins (LSV) in two ...