Prevalence, incidence proportion and independent predictors of thromboembolic events in adults with antiphospholipid syndrome: A systematic review with meta-analysis

Mickael Essouma, Jan René Nkeck, Valirie N. Agbor, Paul Tchaptchet, Ulrich David Dalle, Jessica Claudine N. Yondo, Leticia Armelle Sani Tchouda, Yvan Claude Bernard Momo, Daniel Akoa Akoa, Jériel Pascal Nkeck, Network of Immunity in Infection, Malignancy and Autoimmunity , Universal Scientific Education and Research Network , Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Regional Hospital Centre, Nuffield Department of Population Health, University of Oxford, Population Health Research, Heartsavers Initiative, St Blaise Catholic Hospital, North Ossetia State Medical Academy, Faculty of Health Sciences, University of Buea, Université Libre de Bruxelles, Department of Cardiology, Faculty of Health Sciences, University of Lome, Department of Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I

Phlebology: The Journal of Venous Disease

Published online on January 10, 2026

Abstract

Phlebology, Ahead of Print.
ObjectivesTo synthesize data on the prevalence, incidence proportion, and independent predictors of thromboembolism in adults with definite antiphospholipid syndrome (APS) and those with ‘seronegative APS’.MethodsThis systematic review and meta-analysis ...