The immunomodulatory effect of continuous ultrafiltration during pediatric cardiac surgery

Joel David Bierer, Roger Stanzel, Mark Henderson, John Sapp, Pantelis Andreou, Jean S. Marshall, David Horne, Division of Cardiac Surgery, Dalhousie University, Department of Clinical Perfusion, Nova Scotia Health Authority, Division of Cardiology, Dalhousie University, Department of Community Health , Dalhousie University, Department of Microbiology , Dalhousie University

Perfusion

Published online on September 01, 2025

Abstract

Perfusion, Ahead of Print.
BackgroundCardiopulmonary bypass is associated with systemic inflammation during pediatric cardiac surgery and features elevated systemic concentrations of complement, cytokines and chemokines. The objective of this study is to quantify the immunologic ...