Impact of changes in cardiopulmonary bypass circuit design on pressure loss, wall shear stress, and venous drainage flow

Noriaki Sakai, Takuya Ishigami, Naoto Hagino, Taisei Yamaguchi, Miho Takimoto, Tomoyuki Goto, Masafumi Matsumura, Faculty of Health and Medical Sciences, Department of Clinical Engineering, Kanagawa Institute of Technology, Faculty of Engineering, Department of Mechanical Engineering, Kanagawa Institute of Technology, Department of Clinical Engineering, Kyoto Daini Red Cross Hospital, Department of Cardiovascular Surgery, Kyoto Daini Red Cross Hospital, Division of Biomedical Engineering, Graduate School of Biomedical Engineering, Osaka Electro-Communication University

Perfusion

Published online on October 09, 2025

Abstract

Perfusion, Ahead of Print.
IntroductionBlood damage during cardiopulmonary bypass can trigger postoperative inflammatory responses and organ injury. Therefore, optimizing the blood circuit design to minimize damage remains essential. However, variations in venous drainage circuit ...