Nitric oxide delivery into the sweep flow of ECMO systems: Technical challenges and solutions

Adrian C Mattke, Kerry Johnson, Giles J Peek, Prem Venugopal, Steve Horton, Paediatric Intensive Care Unit, Queensland Children, s Hospital, School of Medicine, University of Queensland, Child Health Research Center, University of Queensland, Department of Cardiaothoracic Surgery, Queensland Children, s Hospital, Congenital Heart Center, University of Florida, Department of Cardiothoracic Surgery, Royal Children, s Hospital

Perfusion

Published online on January 07, 2026

Abstract

Perfusion, Ahead of Print.
Sweep gas nitric oxide (sNO) is emerging as an adjunctive therapy, which may have positive impacts on thrombosis and inflammation during ECMO treatment. sNO is administered to the gas phase of the ECMO oxygenator with the aim of reducing contact ...