Nitric oxide in the ECMO circuit as a treatment option for heparin-induced thrombocytopenia: A case report

Daniel Joelsons, Leonardo Van de Wiel Barros Urbano Andari, Pedro Paulo Zanella do Amaral Campos, Caroline Gomes Mól, Bruno de Arruda Bravim, Giles J Peek, Hospital Israelita Albert Einstein, São Paulo, Congenital Heart Center, University of Florida, Fl Usa

Perfusion

Published online on January 31, 2026

Abstract

Perfusion, Ahead of Print.
IntroductionExtracorporeal membrane oxygenation (ECMO) involves the use of a synthetic circuit, which initiates a complex interplay of inflammatory and pro-coagulant responses. This intricate, self-reinforcing process results in a prothrombotic state, ...