Role of argatroban infusion in controlling clot formation in post-cardiac surgical extracorporeal membrane oxygenation in pediatrics: A case series of three patients

Lara Majdi Samhan, Muhammad Shahzad, Ashjan Alghanem, Reem Beheri, Yasser Alheraish, Abdul Rehman Zia Zaidi, Zainudheen Faroog, Khaled Alarwan, College of Medicine, Alfaisal University, Saudi Arabia, Department of Pediatric Critical Care, King Faisal Specialist Hospital and Research Center, Saudi Arabia, Department of Family , Community Medicine, College of Medicine, Alfaisal University, Saudi Arabia

Perfusion

Published online on February 09, 2026

Abstract

Perfusion, Ahead of Print.
Anticoagulation in pediatric patients on extracorporeal membrane oxygenation (ECMO) presents significant challenges. Direct thrombin inhibitors (DTIs), such as argatroban, are increasingly considered when heparin is ineffective or contraindicated. However,...