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Safety and Efficacy of Intra-articular Cell-Free Fat Extract Injection in Patients With Symptomatic Knee Osteoarthritis

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Orthopaedic Journal of Sports Medicine

Published online on

Abstract

Orthopaedic Journal of Sports Medicine, Volume 14, Issue 4, April 2026.
Background:Cell-free fat extract (CEFFE) has shown promising therapeutic effects on osteoarthritis (OA) in preclinical studies, but its clinical role remains unclear.Purpose:To evaluate the safety and efficacy of intra-articular autologous CEFFE ...