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Low-carbohydrate and high-protein diet may impair working memory via downregulation of hypothalamic T1R3 in mice

Nutrition and Health

Published online on

Abstract

Nutrition and Health, Volume 32, Issue 2, Page 407-412, March 2026.
BackgroundLow-carbohydrate, high-protein (LC-HP) diet declines working memory function in wild-type mice. Since the glucose sensor T1R3 is critical for cognitive function, it was unknown whether the LC-HP diet-induced memory declines involve altered brain ...