Levodopa-Based Therapy in Stroke Rehabilitation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Joseph Y. Bena Nnang, Favour M. L, Samuel G. J, Dimitri S. Tcheuko, Best C. I, Tanyiche C. Agelanu, Joel G. Konlack Mekontso, Ignatius Esene

Neurorehabilitation and Neural Repair: An International Journal of Translational Science for Researchers and Clinicians

Published online on April 04, 2026

Abstract

Neurorehabilitation and Neural Repair, Ahead of Print.
BackgroundThe dopaminergic system plays a key role in neuroplasticity and motor learning, suggesting that levodopa can enhance recovery after stroke. However, the clinical evidence is inconsistent. This systematic review and meta-analysis aimed to provide ...