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A Pragmatic Bayesian Adaptive Trial Design Based on the Value of Information: The Value-Driven Adaptive Design

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Medical Decision Making

Published online on

Abstract

Medical Decision Making, Volume 46, Issue 5, Page 560-574, July 2026.
BackgroundClinical trial designs are typically narrowly focused on error control in hypothesis testing, but this approach is inadequate in many contexts, particularly when a decision maker intends to, or must, consider multiple relevant clinical and ...